Tommy Matisse is a gifted musician studying at London's Royal Academy of Music, where he is striving to write a brilliant new operatic song called "" in conjunction with his girlfriend Alysse back in Australia. When Tommy's sister Emma dies of a drug overdose after a night of clubbing with Alysse, he returns to Melbourne and breaks up with Alysse when she admits her part in Emma's death. As Alysse seeks solace in drugs and in the arms of a manipulative nightclub owner, Tommy undertakes an odyssey of self-discovery and tragedy in Melbourne's dance music scene. Fate brings them together again when Tommy reworks their opera by infusing classical music with electronic beats, but further tragedy is just around the corner...